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Search Results for " free fatty acids "

20

Compounds

Cat No. Product Name Synonyms Targets
T8642 4-CMTB GPR
4-CMTB is a selective agonist of FFA2 and GPR43.It also is a positive allosteric modulator (pEC50=6.38).
T21729 (±)-Lisofylline Others
(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent.
T27439 GS-9667 CVT-3619,CVT 3619 Adenosine Receptor
GS-9667, a selective and partial agonist of the A(1) adenosine receptor (AR), represents an effective therapy for Type 2 diabetes (T2DM) and dyslipidemia via lowering of free fatty acids (FFA).
T3433 TUG-891 TUG 891,TUG891 GPR
TUG-891 is a G protein-coupled receptor (GPCR) expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids.
TN1644 Flavanomarein Others
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...
T5227 Tricaprin Tridecanoin,Glyceryl tridecanoate,Glycerol Tridecanoate,TG(10:0/10:0/10:0),Glycerol tricaprate Others , Endogenous Metabolite
Tricaprin (Glycerol Tridecanoate) is also known as triacylglycerols or triacylglycerides. The triglycerides are rebuilt in the blood from their fragments and become constituents of lipoproteins, which deliver the fatty a...
T2P2919 (2S,3R,4S)-4-Hydroxyisoleucine (4S)-4-Hydroxy-L-isoleucine,Hydroxyisoleucine PI3K
(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secr...
T4903 Heptadecanoic acid Others , Endogenous Metabolite
Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many "odd" length long chain amino acids are derived from the consumption of dairy fats (milk and meat). Heptadecanoic acid constitutes 0.61% o...
T27228 E-3030 free acid E-3030,E3030,E 3030
E-3030 free acid is a peroxisome proliferator-activated receptor (PPAR) agonist. E-3030 decreased blood glucose, triglyceride, non-esterified fatty acids, and insulin levels and increased blood adiponectin levels. Trigly...
T69824 PSB-17365
PSB-17365 is a potent GPR84 agonist. PSB-17365 exhibits EC50 values vs. GPR84 of 2.5nM in a cAMP accumulation assay, and 100nM in a β-arrestin 2 recruitment assay. No direct binding affinities are provided. PSB-17365 is ...
T72745 Acipimox sodium K-9321 sodium
Acipimox (K-9321) sodium, a nicotinic acid analogue, functions as an antilipolytic agent by stimulating leptin release, inhibiting lipolysis, and reducing systemic free fatty acids (FFAs) levels, thereby enhancing insuli...
T37556 CAY10502
Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position leading to the production of lysophospholipids and free fatty acids. Calcium-dependent cytosolic PLA2 (cPLA2α) is a 85 kDa enzyme tha...
T35791 Palmitic acid-13C
Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid i...
T36175 AAPH
AAPH is a water-soluble azo compound which is used extensively as a free radical generator, often in the study of lipid peroxidation and the characterization of antioxidants.[1],[2],[3],[4] Decomposition of AAPH produces...
T69395 Nicotinamide-d4
Nicotinamide-d4 is intended for use as an internal standard for the quantification of nicotinamide by GC- or LC-MS. Nicotinamide is an amide form of niacin, which is also known as vitamin B3, that can be biosynthesized i...
T36830 9-Nitrooleate
Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate , cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. LNO2 isomers serve as p...
T36605 (±)5-iPF2α-VI (±)5-iPF2α-VI
Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation. Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can...
T83906 Tirzepatide sodium LY3298176
Tirzepatide acts as an agonist for both the glucagon-like peptide 1 receptor (GLP-1R) and G protein-coupled receptor 119 (GPR119), effectively inducing cAMP production in HEK293 cells that express either human GLP-1R or ...
T35800 MD001
MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ.1 It binds to PPARα and PPARγ (Kds = 9.55 and 0.14 μM, respectively) but does not bind to PPARβ/δ at concentrations up to 500 μM. ...
T35961 Prostaglandin Bx
PGBx is a mixture of oligomers of PGB1 with a molecular weight of 1,000-1,500. It has antioxidant and free radical trapping activity that was first studied in isolated mitochondria.1 PGBx has anti-inflammatory and cytopr...
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